Tramadol and its metabolite, O-desmethyltramadol (M1), are present in human milk. There's no information on the effects from the drug on the breastfed infant or the effects of the drug on milk manufacturing. The M1 metabolite is much more strong than tramadol in mu opioid receptor binding [see Scientific Pharmacology https://jaspermesfq.ltfblog.com/36120369/the-basic-principles-of-buy-zopliclone