If a parent from the proband is thought to contain the pathogenic variant discovered while in the proband, the chance into the sibs of inheriting the pathogenic variant is 50%. As a consequence of lowered penetrance, sibs who inherit the pathogenic variant may or may not acquire aHUS (see Penetrance). https://ahus38158.mybloglicious.com/52520811/the-2-minute-rule-for-air-handling-unit-ahu-hire