Mechanism of Motion: Obeticholic acid is an agonist for Farnesoid X Receptor (FXR), a nuclear receptor expressed within the liver and intestine. FXR is a vital regulator of bile acid, inflammatory, fibrotic and metabolic pathways. FXR activation decreases the intracellular hepatocyte concentrations of bile acids by suppressing de novo synthesis https://richardh296xcg0.blogoxo.com/profile